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Original Article
Statistical Analysis of 1,000 Cases of Kawasaki Disease Patients Diagnosed at a Single Institute
Dae Hwan Hwang, Kyoung Mi Sin, Kyong Min Choi, Jae Young Choi, Jun Hee Sul, Dong Soo Kim
Clin Exp Pediatr. 2005;48(4):416-424.   Published online April 15, 2005
Purpose : To find the risk factors associated with coronory artery lesions, non-responsiveness to intravenous immunoglobulin(IVIG) treatment, and recurrences in Kawasaki disease patients. Methods : We retrospectively analyzed 1,000 Kawasaki disease patients who were admitted to Yonsei University Medical Center from September 1990 to December 2003. We compared between responder and non-responder groups to IVIG treatment as well as between relapsed...
Expression of Toll-like Receptor-2 on the Peripheral Blood Monocytes in Kawasaki Disease Patients
Dae Hwan Hwang, Jung Woo Han, Kyung Min Choi, Kyung Mi Shin, Dong Soo Kim
Clin Exp Pediatr. 2005;48(3):315-320.   Published online March 15, 2005
Objective : Toll like receptor(TLR) is known to be involved in innate immunity. Many microbial antigens stimulate TLR, and as a result of intracellular signal transduction, they activate nuclear factor-kB which produces diverse inflammtory cytokines. Until now, many research topics in Kawasaki disease focused on cytokine increasement. In this study, we aim to reveal TLR increasement which might be associated...
Effect of a Flavon Extracted from Artemisia absinthium on Collagen Induced Arthritis in Mice
Kyong Min Choi, Dae Hwan Hwang, Kyung Mi Shin, Do-Young Yoon, Dong Soo Kim
Clin Exp Pediatr. 2004;47(6):677-684.   Published online June 15, 2004
Purpose : In this study, a possible suppressive effect of a flavon extracted from Artemisia absinthium on a mouse collagen-induced arthritis (CIA) model was investigated. Methods : DBA/1 mice were injected intradermally with emulsified chicken type II collagen. Three weeks after immunization, a flavon was introduced p.o. everyday. Clinical incidences of arthritis and arthritis index were measured. Measurement of anti-collagen antibodies...
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